Massive Marantic Pulmonary Embolism
Case description
Marantic pulmonary embolism, also known as nonbacterial thrombotic endocarditis (NBTE), is a rare condition characterized by the formation of small, non-infectious blood clots on the heart's valves. These clots can dislodge and travel through the bloodstream, eventually becoming lodged in the pulmonary arteries, causing pulmonary embolism. Unlike typical pulmonary embolism, which is often caused by blood clots originating in the deep veins of the legs (deep vein thrombosis), marantic pulmonary embolism is primarily associated with underlying medical conditions.
This condition is often seen in individuals with chronic illnesses, such as advanced cancer, autoimmune diseases like systemic lupus erythematosus, or chronic infections. These conditions can lead to an increased risk of clot formation within the heart. The clots that form in marantic pulmonary embolism are composed of platelets and fibrin, rather than bacteria or typical blood clots.
Because marantic pulmonary embolism is often a consequence of an underlying condition, treatment primarily focuses on addressing the underlying disease and managing symptoms. Anticoagulant therapy may be used to reduce the risk of further clot formation, and supportive measures are taken to manage pulmonary embolism symptoms. In some cases, surgical intervention to remove clots or repair damaged heart valves may be necessary.
Overall, marantic pulmonary embolism is a complex medical condition associated with underlying diseases, and its management requires a comprehensive approach to address both the embolism and the root cause.
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