Typical HUS is one of the most common causes of the community acquired acute kidney failure in young children. It is characterized by the microangiopathic hemolytic anemia, thrombocytopenia and renal insufficiency. The most common etiological factor is STEC infection, which primary manifests with diarrhea. Life-threatening multiple organ damage (MOD) with central nervous systems (CNS) involvement develops in some cases, and then the treatment of monoclonal antibody might be considered. A previously healthy 2 years old girl was hospitalized in Children’s Clinical University Hospital with febrile temperature for 4 days, bloody diarrhea, abdominal pain and decreased diuresis followed by anuria.
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