Nephritic Syndrome - Types, Classification, Pathophysiology, Treatment (RPGN, ANCA, Immune Complex)

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"The glomerulus are the functional units of the kidneys. Glomerulonephritis which people know as Nephritic syndrome is caused by inflammation to the glomerulus that results in microscopic or macroscopic haematuria, proteinuria, leukocyturia (without evidence of infection and so is sterile) and hypertension. Other features include AKI from inflammation and depending on the aetiology extra renal involvement such as purpuric rash and arthralgia or even alveolar haemorrhage. It can be caused by a variety of conditions including autoimmune, hereditary, and infectious diseases. Glomerulonephritis is not nephrotic syndrome.

Inflammation of the glomerulus causes glomerulonephritis (nephritic syndrome) this damages the glomerular capillary. The porous basement membrane allows RBC to leak out resulting in haematuria."

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