Treatment for Hypertrophic Obstructive Cardiomyopathy - Alcohol Septal Ablation

Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. Alcohol septal ablation is a catheter-based intervention that relies on the injection of absolute alcohol into the septal perforator to induce a controlled infarction of the hypertrophied septum and consequently abolish the dynamic outflow obstruction. This gradient reduction has been correlated with a significant clinical improvement in the patient’s symptomatology and with left ventricular remodeling. ASA is considered as a therapeutic alternative to surgical myectomy for the treatment of LVOT (left ventricular outflow tract) obstruction. ASA is often the best choice for elderly patients and those having advanced medical conditions who cannot tolerate open surgery.