MEDtube Science 2014 - Alzheimer’s disease and osteoporosis – correlation increasing the risk of life-threatening fractures?

lzheimer’s disease (AD), as well as osteoporosis, appears after the age of 60. It was observed that people with Alzheimer’s disease develop adverse events characteristic for osteoporosis more often in comparison with healthy people of the same age. The aim of the study was to assess whether the two disease entities are interdependent and what factors are associated with this possible relationship . It has been confirmed by numerous reports that a decrease of bone mineral density (BMD), a recognized risk factor of life-threatening fractures, correlates with osteoporosis and Alzheimer’s disease. Loss of body weight and body mass index (BMI) and more frequent depression, which are also common in osteoporosis and AD, predispose to this risk. Discovery of correlation between Alzheimer’s disease and osteoporosis is important not only for understanding the pathogenesis, but also for the development of therapeutic methods in the treatment of both diseases. The papers mentioned above allow one to suppose that AD patients should be subjected to prophylactic measures for prevention of osteoporosis.