Cyclosporine A Improves Pregnancy Outcomes in Women with Recurrent Pregnancy Loss and Elevated Th1/Th2 Ratio

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Clinical Immunology

Case description

Recurrent pregnancy loss (RPL) is a one of the most common obstetrical complications. Since, the successful pregnancy occurs in T helper 2 (Th2)‐dominant situation and since, Th1 type immunity is related to pregnancy failure, we investigated the effects of cyclosporine on Th1 and Th2 cells in RPL women. Totally, 76 RPL patients (38 women as treated group and 38 as control group) were included in this study. Flow cytometry was utilized to analyze the frequency of Th1 and Th2 in blood samples.

 

tags: Cyclosporine immunology education immunology training pregnancy recurrent pregnancy loss

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