Scientists from all over the world report about cases of actinomycosis, which due to non-specific symptoms and rare occurence are beeing wrongly diagnosed as a neoplasm. Read full text »
Osteoporosis is a generalized metabolic bone disease, characterized by low bone mass, impaired microarchitecture of the bone tissue and consequently the increased susceptibility to fracture. It occurs most frequently in women after menopause (postmenopausal osteoporosis). The bones undergo remodeling throughout life. Two processes are responsible for their density – bone resorption stimulated by osteoclasts and bone formation performed by osteoblasts. This fact made these cells the main goal of pharmacotherapy for osteoporosis. Read full text »
Prostate cancer is the most common carcinoma of urogenital organs. It is the second most common cancer occurring among the whole male population. Annually there are 9000 new cases diagnosed and a rising tendency has been observed throughout the last 3 decades. Despite of a wide access to radio- and chemotherapy as well as various hormonal therapies and surgical methods, this neoplasm causes around 8% of all deaths in Poland every year. Scientists from Houston Methodist Hospital in Texas have come up with a new method of prostate cancer treatment which is both effective and safe for the patients. It is based on the modification of cancer cell genes with the use of a virus which causes the immune system of a patient to recognise and attack the infected tumour cells.
It is currently believed that depression may be caused by improper functioning of immune system cells in brain. The scientists from The Hebrew University of Jerusalem claim that treatment of depression may be revolutionized by the use of new psychotropic drugs. The results of the analysis were published in Cell Press in the section Trends in Neurosciences. Read full text »
Cataract is the main cause of both the deterioration of and the loss of eyesight in the world. This, in turn, causes not only a serious disability, but also a lowering of the quality of the patients’ life together with burdening the budget of the developed countries since the disease concerns mainly the aging populations. Until now the only cataract treatment perspective was the use of various surgical methods. This situation can be changed, however, by the discovery of the team of scientists from the University of California in San Diego who have described lanosterol as the potential eye drop ingredient that could contribute to the development of pharmacotherapy of the disorder. Read full text »
An interdisciplinary group of scientists from Boston University School of Medicine has described a new protein named TMIGD1 that proved to be engaged into epithelial cells protection in the renal tubules. This particular protein in the future could become a target of new therapeutic strategies used in patients suffering from both acute and chronic kidney disease. Read full text »
Acute ischemic stroke treatment remains a challenge both for clinicans and the population. Early recognition and treatment has a huge impact on further clinical outcomes. The introduction of clot-busting intravenous tissue plasminogen activator (IV tPA) drug improved the prognosis, but did not assure high recanalization rates. Development of endovascular techniques since 1990’s brought new possibilities for acute large vessel occlusion treatment of intracranial arteries. Promising early outcomes induced several randomized trials to assess efficacy and safety, as well as indications for this new approach. Read full text »
The results of the latest research of the scientists from Medizinische Hochschule in Hannover have been published in Cellular and Molecular Gastroenterology and Hepatology, the journal of American Gastroenterological Association. They inform about a new predictor of interferon responsiveness in chronic HCV infection. It is oxLDL – oxidized fraction of low-density lipoprotein, commonly called “a bad cholesterol”. Read full text »
Inguinal hernia is a problem with which surgeons struggle from the beginning of the history of their profession. The disease affects every fourth person in the general population and it occurs 7 times more frequently in men. Basically, it is a pathological exit of organs through an opening in an abdominal wall in spot called “locus minoris resistentiae”. Inguinal hernia gradually enlarges itself and reduces patient’s quality of life. The most serious complication caused by this disease is the incarceration and strangulation of hernia which is an surgical emergency.
Approximately 9 million people in 2013 were suffering from tuberculosis (TB), of which 1,5 milion died – according to the WHO data. Improper use of antibiotics resulted with new strains of Mycobacterium tuberculosis resistant to isoniazid and rifampicin. Recently, research team from the University of Georgia in Athens has developed a new, small molecule drug that could be used in treatment of multidrug-resistant TB. Read full text »