Potential infectious agents in the pathogenesis of sarcoidosis

Year 2016 has brought new reports on a possible participation of infectious agents in the pathogenesis of sarcoidosis. Chinese scientists have published in the ‘PLoS One’ journal the results of a meta-analysis suggesting a possible contribution of Mycobacteria in the development of the disease. On the other hand, an international team of experts have published in the ‘American Journal of Respiratory Cell and Molecular Biology’ the results of an experiment indicating a contribution of Propionibacterium acnes infection in the pathogenesis of sarcoidosis.

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The role of VDR and ER- α genes in the pathogenesis of osteoporosis.

Osteoporosis is a chronic metabolic disease, leading to increased risk of fractures. The essence of its pathogenesis is a disorder in transformation of the bone tissue, associated with osteoclasts and osteoblasts, which is a constant creation of new bone with tissue resorption at the same time. The balance of this process depends on many factors, eg. hormonal, inflammatory, environmental and genetic. Articles, which lay down the role of genetic factors affecting the occurrence of osteoporosis, appeared mostly at the beginning of the 21st century [1]. 
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