Potential infectious agents in the pathogenesis of sarcoidosis

Year 2016 has brought new reports on a possible participation of infectious agents in the pathogenesis of sarcoidosis. Chinese scientists have published in the ‘PLoS One’ journal the results of a meta-analysis suggesting a possible contribution of Mycobacteria in the development of the disease. On the other hand, an international team of experts have published in the ‘American Journal of Respiratory Cell and Molecular Biology’ the results of an experiment indicating a contribution of Propionibacterium acnes infection in the pathogenesis of sarcoidosis.

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The newest hepatitis C tests may reduce diagnosis in half

iStock_000015704019XSmallAccording to WHO, HCV infection should be diagnosed in 2 steps. The first step is screening and serological test for anti-HCV antibodies. If the result is positive, it is necessary to carry out nucleic acid test for HCV RNA (NAT). It is needed to confirm chronic HCV infection. RNA of virus appears in the plasma 1-2 weeks after infection. RNA level gradually increases, but after some time this level falls and RNA test of HCV could be temporarily negative. HCV antibodies appear in 8-10 weeks after infection.

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