Endometriosis and higher risk of a heart disease – new dependencies

iStock_000024649569XSmallAmerican scientists report that women with endometriosis, who are 40 years old and less, are under greater risk of coronary heart disease. The results of the study were published in Circulation Cardiovascular Quality and Outcomes. Read full text »

Severe form of acne vulgaris – is it helpful in the early diagnosis of endometriosis?

PEndometriosis is a chronic gynecological disease affecting a lot of women. It is defined as a presence of endometrium outside the proper place of occurrence, which is the uterine cavity. It may occur at any age however, it mainly concerns young women in their reproductive period, involving 10 percent of them. Read full text »

Melatonin in the treatment of endometriosis

The researchers from Porto Alegre have completed the phase II clinical trial entitled “Efficacy of melatonin in the treatment of endometriosis” (1). It provides evidence concerning the analgesic effects of melatonin on endometriosis-associated chronic pelvic pain (EACPP). Taking this popular OTC drug for jet lag resulted in an almost 40% reduction of daily endometriosis-related pain scores in comparison to placebo(1). The report is a fruit of research conducted by members of the International Association for the Study of Pain. Read full text »

Resveratrol overcomes endometriosis – women can confirm

Nearly 2 years ago we reported the first study on the association between resveratrol and endometriosis, the disease involving most frequently pelvic pain and infertility (1). The preliminary tests (2) on mice showed that the organic antioxidant poliphenol might have application in therapy of endometriosis. This devious disease seems to escape every treatment option, so the prospect was more than promising. Today we see that resveratrol has come up to our expectations. A group of Brazilian scientists conducted an interesting clinical trial (3) investigating the impact of resveratrol added to conventional oral contraceptives on pain level. In addition the researchers examined the expression of aromatase (enzyme responsible for aromatization of androgens into estrogens) and cyclo-oxygenase-2 in the endometrial tissue. Both tests provide encouraging results. Read full text »

Endometriosis – migraine’s bad sister

The comorbidity of endometriosis and migraine was first discovered in 1975, but until now has not been fully acknowledged. Although both diseases share some epidemiological and clinical features, the nature of their relationship remains unclear. Does endometriosis cause headaches? Or is it migraine that makes endometriosis more detectable? Why do they have so much in common? These issues are discussed in the population-based study performed by Taiwanian scientists, which proves that indeed „women with endometriosis are more likely to suffer from migraines” (1). Read full text »

Endometriosis – novel treatment options – cure the incurable

Approximately 10% women are thought to be affected with endometriosis. An understanding of its pathogenesis seems to be rather poor, though the scale of the problem is large. Limited to conventional hormonal therapies and surgical intervention, women usually suffer from adverse effects that make the disease even more psychically and psychologically debilitating. Recent advances in the field of discovering endometriosis’ etiology lead to surprising findings. The underestimated potential of statins gives hope for their application in endometriosis treatment. New selective estrogen modulators might also come in handy. What is more, the greater insight into the role of stem cells in development of endometrial lesions may result in therapy targets that no one ever thought of. Read full text »

Resveratrol inhibits experimental endometriosis

Latest study shows that resveratrol, red wine derived and known for its anti-inflammatory properties, reduces development and progression of endometriosis in mice model and decreases the invasiveness of endometrial tissue in vitro. Read full text »