Can Hodgkin disease be the causa of permament fatigue?

PHodgkin’s disease is a lymphatic system neoplasm, which can be developed by both – children and adults. The median age at first diagnosis is about 30 years. Permanent fatigue which is recently reported by survivors more frequently, is becoming a serious problem during extensive care of the patient. Read full text »

Endometriosis and higher risk of a heart disease – new dependencies

iStock_000024649569XSmallAmerican scientists report that women with endometriosis, who are 40 years old and less, are under greater risk of coronary heart disease. The results of the study were published in Circulation Cardiovascular Quality and Outcomes. Read full text »

Alfa-L-fucosidase as a new potential marker of non-alcoholic fatty liver disease

Team of doctors.Non-alcoholic fatty liver disease (NAFLD) is currently the most frequent chronic liver disease. Although first mentions of the disease go back to the second half of 20th century, the scientists still find new missing links in pathogenesis chain of NAFLD. A group of researchers from First Affiliated Hospital of Zhejiang University of Medicine in China have shown a positive correlation between level of alpha-L-fucosidase in blood plasma and the risk of non-alcoholic fatty liver disease development [1]. Read full text »

suPAR – a promising marker for chronic kidney disease

iStock_000025954109_XXXLargeA study published in the New England Journal of Medicine shows that suPAR protein (soluble urokinase-type plasminogen activator receptor) is a promising marker of chronic kidney disease risk. Circulating protein can be measured in a blood sample. High level of suPAR can indicate the likelihood of developing chronic kidney disease up to five years before kidney damage will begin.

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Are we already able to prevent kidney damage?

iStock_000025954109_XXXLargeAn interdisciplinary group of scientists from Boston University School of Medicine has described a new protein named TMIGD1 that proved to be engaged into epithelial cells protection in the renal tubules. This particular protein in the future could become a target of new therapeutic strategies used in patients suffering from both acute and chronic kidney disease. Read full text »

Chikungunya – vaccine soon available?

B cell lymphocyte producing antibodiesChikungunya was first described in Tanzania and Uganda in 1953. From its initial outbreaks it spread into Asia and Europe causing more and more incidences every year. The name of the disease comes from Makonde language and means “hump”. It relates to leant body posture stemming from the fact that joints are affected. Scientists from US-National Institute of Allergy and Infectious Diseases from Bethesda work to develop a new vaccine against this fast-spreading disease. In their first clinical trial described by Lancet magazine, they proved that the vaccine is immunogenic, safe and well-tolerated. Read full text »

Parkinson’s disease and pesticides – more and more facts

Brain Specimen and StethoscopeIt has been assumed for years that Parkinson’s disease, which is a degenerative disease of a central nervous system arising from dopamine deficiency, may have other causes than genetic ones. It was thought that risk factors may come from external environment as in the case of many other diseases. Read full text »

Cholinesterase inhibitors – lower risk of heart attack and death in Alzheimer’s disease patients

The group of drugs used in Alzheimer’s disease therapy are cholinesterase inhibitor(ChEI). It turns out that their influence on cranial nerve X and anti-inflammatory action may be useful in prophylaxis of cardiovascular diseases. Authors of a research published in European Heart Journal have shown that ChEI intake may significantly decrease the risk heart attack and death. Read full text »

The first Boston disease vaccine

The latest research conducted by Feng-Cai Zhu et al. from Regional Centre for Disease Prevention and Control in Nanjing have contributed to the development of the first vaccine for human enterovirus 71 (EV-71). The virus is considered to be the main cause of hand, foot and mouth disease. In China over a million of people suffer from it and several hundred die because of it every year. Read full text »

Breakthrough in Parkinson’s disease treatment- gene therapy

American scientists succeeded in developing gene therapy owing to which Parkinson’s disease symptoms recede. The new method reduces movement disorders such as bradykinesia, muscle stiffness and tremor at rest as proved by research published in “Lancet Neurology”. Read full text »