Epidemiologic evidence suggests that diabetes is associated with an increased risk of cancer. Many reports describe numerous mechanisms, which can be the basis for the relationship between diabetes and cancer risk. One of them is the promotion of DNA damage through oxidative stress caused by an increased mitochondrial glucose oxidation. Moreover, insulin resistance, hyperinsulinemia, elevated levels of free insulin‐like growth factor and chronic inflammation associated with diabetes may also explain the positive association between diabetes and cancer risk.
Type II diabetes is a civilization disease of the 21st century. According to statistics, in 2014 the number of people with this disease was 422 million (fourfold increase in the number of patients within 35 years). It is the most common cause of disability and deaths worldwide. It is estimated that the global number of patients will exceed 777 million in 2025. Over 60% of patients report persistent pain, numbness, tingling, burning sensation, tenderness of the skin, especially in the distal parts of the limbs referred to as (poly) diabetic neuropathy.
The research that has recently been published shows that islet transplantation in patients with type 1 diabetes may prevent sugar drops that are dangerous to health. The results of the work of the scientists are considered a breakthrough in the fight against this chronic disease.
Scientists from Catholic University of Rome recently published results of their studies in „The Lancet”. They proved that bariatric surgeries are more effective in treatment of diabetes type 2 in obese patients than pharmacotherapy. Read full text »
The latest research show that 54 million Americans with BMI in the range of overweight or obesity have good test results, what implicates that there is no heart disease or diabetes. On the other hand, Americans with normal BMI have worse results. This could be the beginning of the end of this commonly used indicator. Read full text »
Finnish researchers suggest that there is a link between insulin resistance (typical for type 2 diabetes) and language difficulties in women (a sign of cognitive disorders in dementia). The study included both men and women belonging to different age groups and was conducted by Laura Ekblad Ph.D. and colleagues from the University Hospital in Turku, Finland. The results of the research were published in “Diabetes”, journal of the European Association for the Study of Diabetes.
Millions of patients with diabetes are still waiting for effective and cheap medications. The lack of availability of the newest drugs causes the patients to develop various complications due to the illness. However, a new opportunity has risen to revolutionise the pharmacotherapy of diabetes- scientists from Illinois have recently discovered that herbs which tend to be widely used in our kitchens contain bioactive substances that have a mechanism of action similar to that of incretin drugs. This discovery could provide a possibility of manufacturing cheap medications that could improve the prognosis in diabetic patients. Read full text »
In July 2014 an official magazine of the European Atherosclerosis Society Atherosclerosis has published an article describing scientists from The German Diabetes and Dialysis Study Investigators (4D) who on the basis of conducted research found a close relation between level of PAPP-A marker and specific cardio-vascular complications in dialyzed patients with diabetes. They came into a conclusion that PAPP-A level correlates with sudden death, stroke and infectious complications of diabetes. Read full text »
Increasing number of obese children results in increase of diabetes mellitus type two incidence in youth. In combination with increase of diabetes mellitus type one incidence in adults, differentiation of both types of the disease without expensive, time consuming laboratory tests detecting antibodies characteristic for autoimmunologic diabetes is becoming more and more difficult. Now it can change. Scientists from Stanford University School of Medicine in California have devised cheap, mobile test which bases on nanotechnology in microchip which specificity and sensitivity does not deviate from traditional laboratory tests conducted until now. Read full text »