Rociletinib is a breakthrough in the treatment of Non-small Cell Lung Cancer, isn’t it ?

medical doctor looking at x-ray picture of lungs in hospitalNew targeted therapy directed against mutated Epithelial Growth Factor Receptor (EGFR) in lung cancer, in opposition to the current therapy indicates an activity against most common treatment-resistant mutations as well as significantly improves the prognosis of patients. The results of phase I / II clinical trials of rociletinib were published on the pages of the New England Journal of Medicine on 30 April. The preliminary results were previously presented in 2014 at the congress of the American Society of Clinical Oncology. Read full text »

Stem cells of fat tissue – a new chance in treatment of stress urinary incontinence

iStock_000015704019XSmallKirsi Kuismanen and coworkers from Obstetrics & Gynecology Clinics and Scientific Centre in Tampere University Hospital in Finland have published a research describing new treatment method of stress urinary incontinence in women. It was published in Stem Cells Translational Medicine. The new method uses stem cells coming from fat tissue. Read full text »

Human epidermis was grown from stem cells

In laboratories of King’s College in London it was possible to grow epidermis with the use of stem cells. The epidermis is structurally and functionally similar to native one in humans. It has protective functions and permeability, thus it can be a natural barrier. The research was published in Stem Cell Reports in April 2014. Read full text »

Groundbreaking discovery in the field of somatic cell’s differentiation

The recipients of this year’s Nobel Prize in Physiology or Medicine are John Gurdon and Shinya Yamanaka awarded for their groundbreaking discovery in the field of somatic cell’s differentiation. The scientists have managed to unequivocally prove a possibility of taking any adult cell back in time to a stadium of pluripotential stem cell, which is counter to the previous knowledge and well established rules of biology. Read full text »

Forever young – the elimination of senescent cells reduces the risk of diseases

The issue of aging and the mechanisms directing it has always attracted great interest. This subject is connected with the eternal human desire to prolong life and improve its quality. In May 2011, a team of researchers from the Mayo Clinic of Medicine under the leadership of Darren J. Baker published an article which shows the relationship between the elimination of aging cells from the body and the delay of processes associated with progression of age. Read full text »