Scientists from Australia noticed decreased levels of circulating cancer-associated protein biomarkers after bariatric surgery in obese patients. Many scientific studies proved that there is an association between obesity and risk of cancer development. Read full text »
Epidemiologic evidence suggests that diabetes is associated with an increased risk of cancer. Many reports describe numerous mechanisms, which can be the basis for the relationship between diabetes and cancer risk. One of them is the promotion of DNA damage through oxidative stress caused by an increased mitochondrial glucose oxidation. Moreover, insulin resistance, hyperinsulinemia, elevated levels of free insulin‐like growth factor and chronic inflammation associated with diabetes may also explain the positive association between diabetes and cancer risk.
Cancer chemoprevention involves the chronic administration of natural or synthetic substances to reduce or delay the incidence of malignancy. Research team from University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute investigated the potential chemopreventive activity of sulforaphane, compound obtained from broccoli, against carcinogen-induced oral cancer. The study was recently published in the journal Cancer Prevention Research.< Read full text »
The scientists from the University of Southern California Norris Comprehensive Cancer Center found that drinking coffee, decaffeinated or not, may reduce the risk of colon cancer. The study was published in the journal Cancer Epidemiology, Biomarkers & Prevention. Read full text »
Prostate Cancer (PCa) is statistically one of the most common malignant neoplasms among men. Existing screening programs led to the increased detectability of the tumor in the early clinical stages. Scientifically proven, effective and recommended by the European Association of Urology treatment of PCa in stages confined to the prostate gland is a radical prostatectomy or radiotherapy. Methods yield similar good results, but are fraught with early and late complications. For this reason, the search for alternative solutions to the above methods of treating prostate cancer in a low stage has started. One of such alternative approaches is developed over 15 years HIFU. However, as with any new treatment method in surgery, its efficacy and safety have to be confirmed in numerous scientific studies. One of such studies was conducted by the doctors from the Institut Montsouris in Paris.
The journal Cancer Epidemiology, Biomarkers & Prevention published an article showing the connection between the glycemic index (GI) and an increased risk of lung cancer. This study represents the largest analysis to demonstrate the possible links. Read full text »
Until this day there is no consensus among surgeons which of available ways to reconstruct the continuity of the gastrointestinal tract after subtotal gastrectomy is the best. The most common reasons for performing this surgery are cancer of the distal part of the stomach and perforation of the stomach wall in the course of ulcer disease. Read full text »
The latest research show that patients’ mental health before surgery may influence postoperative results. Radical cystectomy (RC) is a very effective method in in the treatment of locally advanced bladder cancer but complications occur in 66% of patients. American scientists stated that complications occurring within 30 days after the procedure were more frequent in patients with low self-esteem than in those with higher self-esteem. The results were published in The Journal of Urology. Read full text »
Cancer cachexia is one of the main problems in the treatment of patients with advanced cancer. As shown by the most recent studies conducted by researchers at The Ohio State University Comprehensive Cancer Center – The James Cancer Hospital and Solove Research Institute (OSUCCC – James), a new inhibitor of histone deacetylases – AR-42 raises huge hopes in the world of oncology. New findings demonstrate that AR-42, through its inhibitory effect on the production of proinflammatory cytokines and multiple procachectic factors, can prevent body weight loss, muscular atrophy and reduction of adipose tissue mass. The results of this promising research were published in the renowned The Journal of the National Cancer Institute magazine . Read full text »
Prostate cancer is the most common carcinoma of urogenital organs. It is the second most common cancer occurring among the whole male population. Annually there are 9000 new cases diagnosed and a rising tendency has been observed throughout the last 3 decades. Despite of a wide access to radio- and chemotherapy as well as various hormonal therapies and surgical methods, this neoplasm causes around 8% of all deaths in Poland every year. Scientists from Houston Methodist Hospital in Texas have come up with a new method of prostate cancer treatment which is both effective and safe for the patients. It is based on the modification of cancer cell genes with the use of a virus which causes the immune system of a patient to recognise and attack the infected tumour cells.