Osteoporosis is a generalized metabolic bone disease, characterized by low bone mass, impaired microarchitecture of the bone tissue and consequently the increased susceptibility to fracture. It occurs most frequently in women after menopause (postmenopausal osteoporosis). The bones undergo remodeling throughout life. Two processes are responsible for their density – bone resorption stimulated by osteoclasts and bone formation performed by osteoblasts. This fact made these cells the main goal of pharmacotherapy for osteoporosis. Read full text »
According to the latest research led by scientists from University in Sheffield benign forms of Osteogenesis imperfecta (OI, brittle bone disease) may be treated with bisphosphonates administered orally. The number of broken bones in patients subjected to the therapy decreased significantly. The results of the scientists’ work were published in prestigious science magazine The Lancet. Read full text »
On the 7th International AIDS Society Conference in Kuala Lumpur doctor Timothy Henrich and Daniel Kuritzkes from Brigham and Women’s Hospital, Boston, announced that after a bone marrow transplant in two HIV infected patients the virus was not detected in their peripheral blood. This report had galvanized the whole medical world because complete recovery from HIV is extremely difficult. Currently, the treatment is limited to antiretroviral drugs (ART) which inhibit virus replication. However, the therapy which would guarantee complete healing is not known.
Randomized research of the scientists from Canada aimed to show the influence of calcium on the length of life allows to say that increased consumption of calcium-rich products positively influences the decrease of morbidity in women. Read full text »
Crocodile teeth grow continuously throughout the animal’s life. When a bad tooth falls out, a new one grows immediately in its place. This phenomenon has inspired scientists to look for a new breed of human laboratory-grown teeth. So far, the success could already be claimed by a number of research groups over the globe. The results of the experiments however did not give a hope for the use of this phenomenal approach in the dental clinics in a large-scale. King’s College in London, however, has set an important milestone on the way to the true immortality of our smile. Read full text »
Dental implant treatment is becoming more popular around the world, often replacing traditional prosthetic treatment. Dental implant market is growing rapidly. Unfortunately, for some patients this treatment is not available due to systemic and local contraindications. With the discovery of the Universitat Jaume I scientists in Castellón comes a great oportunity for a group of patients who have been refused a dental implant treatment before.
Scientists from Switzerland and United Arab Emirates made a research thus proving that taking cholecalciferol (vitamin D) is an effective analgesic therapy. Read full text »
Vitamin E, which is commonly considered to have positive influence on reproduction, was subjected to analysis by Japanese scientists who stated that it reduces the bone mass. The results of their research were published in “Nature Magazine” in 2012. Read full text »
Osteosarcoma is the most common primary bone tumour. It is characterized by the presence of the fusiform cells producing a malignant extracellular osteoid. Both, the malignancy and the ability to create metastasis depend on the histological type. Osteosarcoma is an eighth most common tumour in infants with a peak of incidence between 10 and 14 years. Nevertheless, we should not forget that osteosarcoma is also an adult cancer. In this case it can occur either as an idiopathic or as a secondary disease (e.g. to Paget disease).
Fibrydysplasia (FOP) is a rare genetic disorder, in which the organism products extra bones in places where they should not develop. These bones are produced within the muscles, tendons, ligaments and other connective tissues. They cause ossification in various places hindering the normal functioning of the person. Read full text »