Prostate Cancer (PCa) is statistically one of the most common malignant neoplasms among men. Existing screening programs led to the increased detectability of the tumor in the early clinical stages. Scientifically proven, effective and recommended by the European Association of Urology treatment of PCa in stages confined to the prostate gland is a radical prostatectomy or radiotherapy. Methods yield similar good results, but are fraught with early and late complications. For this reason, the search for alternative solutions to the above methods of treating prostate cancer in a low stage has started. One of such alternative approaches is developed over 15 years HIFU. However, as with any new treatment method in surgery, its efficacy and safety have to be confirmed in numerous scientific studies. One of such studies was conducted by the doctors from the Institut Montsouris in Paris.
The latest research show that patients’ mental health before surgery may influence postoperative results. Radical cystectomy (RC) is a very effective method in in the treatment of locally advanced bladder cancer but complications occur in 66% of patients. American scientists stated that complications occurring within 30 days after the procedure were more frequent in patients with low self-esteem than in those with higher self-esteem. The results were published in The Journal of Urology. Read full text »
Prostate cancer is the most common carcinoma of urogenital organs. It is the second most common cancer occurring among the whole male population. Annually there are 9000 new cases diagnosed and a rising tendency has been observed throughout the last 3 decades. Despite of a wide access to radio- and chemotherapy as well as various hormonal therapies and surgical methods, this neoplasm causes around 8% of all deaths in Poland every year. Scientists from Houston Methodist Hospital in Texas have come up with a new method of prostate cancer treatment which is both effective and safe for the patients. It is based on the modification of cancer cell genes with the use of a virus which causes the immune system of a patient to recognise and attack the infected tumour cells.
Scientists from the University of Southern California have found a new target for prostate cancer drugs – it is recently discovered GPR 158. It has been demonstrated that increased expression of GPR 158 correlates with worse prognosis and hyperproliferation of prostate cancer cells.
Researchers from Imperial College of London and University of Crete found that urine testing for the presence of specific metabolites in pregnant women can help in the diagnosis of preterm birth or fetal growth restriction. In the future, by identifying metabolic profiles in the urine of pregnant women it will be possible to reduce complications resulting from premature birth. The study was published in the journal BMC Medicine. Read full text »
Does vaccine created by researches from Washington University School of Medicine (Saint Louis) can help to reduce catheter-associated urinary tract infection? New studies published in Science Translational Medicine seem to be promising. Read full text »
Pelvic congestion sydrome (PCS) presents with noncyclic lower abdominal or pelvic pain that persists for longer than 6 months. The pain-related symptoms are described as a dull ache or fullness that can last for many hours or even days. The underlying pathology consists on pelvic varicosities. The current treatment methods include painkillers as symptomatic management. The contraceptives are administered for pain treatment related with menstruation. If these methods are insufficient, the invasive approach is suggested. Until the interventional radiology development, a total histerectomy has been performed. Despite of total uterus removal, the pain reduction was not observed in each case. Read full text »
Kirsi Kuismanen and coworkers from Obstetrics & Gynecology Clinics and Scientific Centre in Tampere University Hospital in Finland have published a research describing new treatment method of stress urinary incontinence in women. It was published in Stem Cells Translational Medicine. The new method uses stem cells coming from fat tissue. Read full text »
A team of scientists from United States led by professor Gangning Liang from the Department of Urology at USC Norris Comprehensive Cancer Center have discovered methylation markers in urine sediment of patients suffering from non-muscle invasive bladder cancer. Presence of the markers may help to predict recurrence of the cancer. Research was published in Clinical Cancer Research magazine. Read full text »
A new study of Swedish researchers, recently published in the ‘European Urology’ journal, proposes to introduce a “genetic score” based on the analysis of single nucleotide polymorphisms (SNPs) to identify men at high risk of developing prostate cancer, whose serum PSA concentration is within the limits of 1-3 ng/ml (gray range). In this concrete group of patients a prostate biopsy would be indicated. Read full text »