Herpes viruses – hope for melanoma patients

iStock_000034756166_DoubleMelanoma originates from pigment cells – melanocytes. Melanoma is the main cause of deaths of skin neoplasms. It is one of the most refractory neoplasms. Many scientific reports indicate the possibility of using the virus as a weapon against cancer, especially in inoperable cases. Read full text »

Botulinum toxin – a new method in long-term prevention of recurring atrial fibrillation

iStock_000055110862_XXXLargeBotulinum toxin (botox, BTX) and bacteria which produce it were identified for the first time in 1897 by Belgian bacteriologist Emile Pierre van Ermenghen [1]. Although many decades have passed since this historical moment, its “hidden” properties are still an unsolved mystery. However, already today it can be said that botulinum toxin is an amazing substance. The best evidence of that are results of research published on 20th October 2015 in American magazine Circulation: Arrhythmia and Electrophysiology. On the basis of conducted randomized study it was shown that in the nearest future botulinum toxin may be used on a large scale in long-term prevention of paroxysmal atrial fibrillation recurrence (PAF), especially in patients after cardiac surgeries [2]. Read full text »

Occupational exposure to ultraviolet radiation as a risk factor of melanoma development

iStock_000017040940_LargeSo far, people working on the land, skiing instructors, and sportsmen were considered to be at higher risk of melanoma development because of occupational exposure to UV radiation. In their latest research, scientists from University of California in San Francisco proved that also pilots and flying personnel are at risk of melanoma development and they suffer from it twice more often than average population. Research was published in Jama Dermatology magazine. Read full text »

Botox – an effective remedy for stomach cancer?

Botox, which is a botulinum toxin, has been inextricably connected with medicine for many years. It was first used in ophthalmology and neurology in early 1920s. Currently, it became an integral part of beauty parlors and salons. Scientists from Columbia University in New York and Norges Teknisk-Naturvitenskapelige Universitet in Trodheim in cooperation with researchers from Germany, Japan and Massachusetts Institute of Technology in Boston during their research on three mice models of stomach cancer have discovered that vagus nerves have a significant influence on the development of the cancer in its all stages and botulinum toxin, due to its properties, can block nerves thus contributing to increase of the chances to cure the disease. Read full text »

Human epidermis was grown from stem cells

In laboratories of King’s College in London it was possible to grow epidermis with the use of stem cells. The epidermis is structurally and functionally similar to native one in humans. It has protective functions and permeability, thus it can be a natural barrier. The research was published in Stem Cell Reports in April 2014. Read full text »

Cyclosporine in the treatment of atopic dermatitis

Cyclosporine is an immunosuppressive drug. Since 1983 is used as prophylaxis in patients after transplantation what increases the post-transplantation survival rate and improves patient’s quality of life. Although the drug was discovered in 1970 and 1973 was used to treat psoriasis, it is more commonly associated with transplantology. (1) Cyclosporine inhibits humoral and cellular components of inflammatory response. That is why it is also used not only in the treatment of chronic inflammatory and autoimmune diseases such as rheumatoid arthritis or psoriasis, but also in severe atopic eczema which is resistant to other treatment. Read full text »

The first Boston disease vaccine

The latest research conducted by Feng-Cai Zhu et al. from Regional Centre for Disease Prevention and Control in Nanjing have contributed to the development of the first vaccine for human enterovirus 71 (EV-71). The virus is considered to be the main cause of hand, foot and mouth disease. In China over a million of people suffer from it and several hundred die because of it every year. Read full text »

Hibiscus-derived gossypin fights melanoma

The end of March and the beginning of April brought the discovery (1) of Texas scientists to light. The researchers tested a little known substance – gossypin – for its action against skin cancer cells. This naturally-occurring flavone was found to inhibit in vitro human melanoma proliferation. Scientists have also observed a unique mechanism that may be responsible for this effect. Furthermore, gossypin therapy, carried out on mice model, reduced the size of melanoma tumors and increased the survival rates. And this is not the only secret property that this flower-derived flavone has. Read full text »

Remission of malignant melanoma is possible

Scientists from Memorial Sloan Kettering Cancer Center performed a study on one patient, to assess the role of the immune system in the fight against cancer. The results were published in the New England Journal of Medicine as a brief report. Ipilimumab (CTLA-4 protein blocker) was administered to patient with malignant melanoma. An unusual phenomenon was observed, in which radiation therapy of one cancer site, resulted in disappearance of metastatic tumors within whole body.

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Skin in spray for leg ulcers

Chronic venous leg ulcers are becoming more prevalent, but the standard treatment heals only approximately half of lesions (1). What to do when the small vessels are damaged and the tissue inflammation is hard to stop? American scientists believe in the cell therapy. Their long-standing research resulted in the study (2) of spray-applied human allogeneic fibroblasts and keratinocytes. The paper was published in the August issue of the Lancet. The researchers avoided expensive tissue engineering and still achieved therapeutic success. Soon the greater circle of patients might benefit from this new method. Read full text »