A 26 year-old man, who was under course of antibiotic therapy underwent a watery diarrhea and sepsis. Typical pseudomembranes adherent to the colonic mucosa in antibiotic-associated colitis. The...
A 43 year-old woman, Suffering of deformed rheumatoid arthritis, underwent a cholecystectomy. Broad-spectrum antibiotics were administered, and one week after she was released from the hospital, she...
(Third Look) Pseudomembranous colitis was first described in 1893 when a patient with severe diarrhea was found to have "diphtheritic colitis" at autopsy. The condition was attributed to mucosal...
Unproven therapies Tapering course of standard antimicrobials Yeast (Saccharomyces boulardii) with AB Cholestyramine Lactobacillus acidophilus Nontoxigenic C. difficile (oral) Bacterial enemas Rectal...
Confusing Terminology Antibiotic-associated diarrhea C. difficile is only one cause Clostridium difficile-associated diarrhea diarrhea + positive stool test Clostridium difficile colitis underlying pathologic...
Clostridium difficile infection (CDI) is a frequent cause of morbidity and mortality among elderly hospitalized patients. A small but increasing number of patients have developed fulminant CDI, and...
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