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Lung, Kidney - Metastatic Calcification

Washington Deceit

Identify the calcifications. Where are they? What would you expect the patient's serum calcium level to me in metastatic calcification?

views: 1102 comments: 0

Liver, Lymph Node - Hemochromatosis - Hemosiderosis

Washington Deceit

What stain might you suggest to prove that the golden brown intracellular pigment is hemosiderin and not bile or melanin? Find some. Can severe iron deposition cause portal fibrosis and regenerating nodules?...

views: 2631 comments: 0

Liver - Fatty Change 3

Washington Deceit

What percentage of this liver's weight might you guess would be fat? Is the overall portal architecture still preserved? Is there inflammation? Is there neoplasm?

views: 1259 comments: 0

Liver - Hemochromatosis

Washington Deceit

Differentiate hemosiderosis from hemochromatosis. Which is worse? Name three common substances that stain golden brown by routine stains? How do you prove it might be hemosiderin? What stain might you...

views: 1322 comments: 0

Liver - Fatty Change 2

Washington Deceit

What are the two most common causes of fatty liver, by far? Is fatty change, fatty metamorphosis, and steatosis, all terms for the same thing? What color might this liver be grossly? Why? Might it look...

views: 1019 comments: 0

Liver - Fatty Change

Washington Deceit

What is MICRO-vesicular fat? How does it differ from MACRO-vesicular? Which one is more advanced? Point out a microvesicle.

views: 1196 comments: 0

Cholestasis

Washington Deceit

Liver--Cholestasis What is the definition of cholestasis? Find some bile lakes here. What is a bile lake? What are common causes of cholestasis? What is the common denominator for all cholestasis?

views: 1470 comments: 0

Alcoholic Liver Disease

Washington Deceit

Can the terms alcoholic hyaline and Mallory body be used interchangeably? What is it? Find some. How does it differ from a Councilman body Is fat a major finding of alcoholic hepatitis? Is it commonly...

views: 1503 comments: 0

Arteries - Arterio- And Arteriolo-Sclerosis

Washington Deceit

What is the difference between arterial sclerosis and arteriolar sclerosis? Are they related to atherosclerosis? Are they part of atherosclerosis? Point out an example of each

views: 1244 comments: 0

Kidney - Nephrocalcinosis

Washington Deceit

Does metastatic calcification mean metastatic disease is present? How does it differ from dystrophic calcification? Demonstrate some calcified areas within tubules?

views: 1777 comments: 0

Interphalangeal Joint Of Toe - Gout

Washington Deceit

What is a tophus? What kinds of cells and tissues comprise it? Point out the foreign body type giant cells. Encircle a tophus. Why is formalin fixation not ideal for tophus specimens? associated with?...

views: 1587 comments: 0

Gallbladder - Cholesterolosis

Washington Deceit

Show the cholesterolosis areas? Which part of the gallbladder wall is it found in. What is it highly associated with? What kind of calculi are found, very often, with cholesterolosis, yellow or green?...

views: 2669 comments: 0

Barrett Esophagus 2

Washington Deceit

Define intestinalization of esophageal mucosa. Show it on this slide. What is, by far, the most common cause of a Barrett esophagus?

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Barrett Esophagus

Washington Deceit

Should all esophageal mucosa, ideally, be squamous? What do you call it when it is replaced by glandular, i.e., gastric or intestinal, type of mucosa? A long standing Barrett esophagus presents a statistical...

views: 1362 comments: 0

Endometrium - Senile Atrophy

Washington Deceit

What is the normal thickness of the endometrium, in mm. during an endometrial monthly cycle? What is an average thickness of an endometrium in atrophy, in mm.? Are actual endometrial glands sparse here?...

views: 1700 comments: 0

Endometrium - Hyperplasia

Washington Deceit

What is hyperplasia defined as anywhere in the body? Are almost all the glands here at least separated from other glands by at least a small amount of connective tissue, i.e., stroma? Most hyperplasias...

views: 1341 comments: 0

Coronary Artery - Atherosclerosis - Recanalization

Washington Deceit

What is recanalization? Demonstrate it. What percentage of the lumen is compromised in this slide?

views: 1970 comments: 0

Coronary Arteries - Atherosclerosis

Washington Deceit

Find cholesterol clefts. Delineate the thickness of the plaque. What is a plaque? What kinds of things is it commonly composed of? What percentage of the lumen is narrowed, i.e., compromised?

views: 1371 comments: 0

Cervix - Squamous Metaplasia

Washington Deceit

Encircle an area of squamous metaplasia. Encircle an area of squamous cell carcinoma-in-situ. What is the difference? Does metaplasia usually precede squamous cancer? Does most metaplasia develop into...

views: 4009 comments: 0

Cervix - Atrophy

Washington Deceit

Is this a tissue section or a smear of an epithelial surface? What famous doctor is this smear named after? In most non-atrophic normal Pap smears the predominant cell is a small nucleated abundantly...

views: 1772 comments: 0

Breast - Hyperplasia Of Lactation

Washington Deceit

What is the eosinophilic material distending many acini? Show it. Is this glandular/stromal cross-sectional ratio higher than the previous slide? Why?

views: 1166 comments: 0

Breast - Hyperplasia Of Pregnancy

Washington Deceit

What percentage of this breast tissue is glands (vs. stroma or connective tissue)? What is a normal percentage for premenopausal, non-pregnant adult women, pregnant women, lactating women, and postmenopausal...

views: 911 comments: 0

Bone Marrow - Erythroid Hyperplasia

Washington Deceit

What is the normal ratio of marrow cells to fat in an average normal adult hematopoetic bone marrow? What is the ratio here? What is the normal ratio of myeloid cells to erythroid cells in an average...

views: 2246 comments: 0

Bone - Hyperparathyroidism

Washington Deceit

Name some common causes of hyperparathyroidism. What is the normal weight of a single parathyroid gland? Are most causes of hyperparathyroidism associated with an increase in parathyroid gland weight?...

views: 1050 comments: 0

Aorta - Atherosclerosis 2

Washington Deceit

Point out cholesterol clefts, ulceration (of intima), and dystrophic calcification. Is dystrophic calcification usually associated with hypercalcemia? Is the other type of calcification, metastatic...

views: 1299 comments: 0

Aorta - Atherosclerosis With Fatty Streak

Washington Deceit

Encircle the fatty streak. What is its significance? Is a fatty streak the earliest grossly recognizable finding of atherosclerosis? At what age can fatty streaks be identified in most Americans? What...

views: 1842 comments: 0

Adrenal - Atrophy

Washington Deceit

Demonstrate the thickness of the adrenal cortex. Does the general term adrenal atrophy usually refer to the cortex or medulla? Could the term hypoplasia apply here as well? Name 2 common causes of cortical...

views: 1172 comments: 0

Stomach - Erosion

Washington Deceit

Draw a line delineating the precise area of epithelial loss. Do you think the term erosion, in this case, can be, more or less, interchangeably, used with the term ulceration?

views: 2077 comments: 0

Soft Tissue - Foreign Body Reaction

Washington Deceit

Foreign body tissue reactions almost always involve which types of cells? What is the derivation of these cells? Point arrows to a bunch of them. Do you think you can often see the actual foreign material...

views: 1089 comments: 0

Duodenum - Chronic Peptic Ulcer - Penetrating

Washington Deceit

Demonstrate several processes which justify NOT calling this ulcer acute? Draw a line where the mucosa ends.

views: 1271 comments: 0

Duodenum- Peptic Ulcer

Washington Deceit

What percentage of the normal thickness of this duodenal wall (4 layers) has been compromised by this ulcer, 10Andpercnt;, 50Andpercnt;, 90Andpercnt;? Draw a line showing the thinnest part. What do...

views: 1225 comments: 0

Small Intestine- Crohn Disease

Washington Deceit

Which 4 layers of the GI wall are classically involved by Crohn (or more commonly Crohns or Crohn's) disease, one or most? What single small histopathologic structure is almost diagnostic of Crohn disease?...

views: 1753 comments: 0

Skin - Ulcer - Amputation Stump

Washington Deceit

What is the definition of an ulcer anywhere in the body? Draw a line where the viable appearing epithelium ends and the inflammatory tissue starts.

views: 1293 comments: 0