Vitamin D Status in Surgical Patients – Own Experience

Abstract: Vitamin D plays an important role in calcium homeostasis. It has a pleiotropic health effect. Vitamin D deficiency is a risk factor for cardiovascular and immune diseases, infections, cancers and mental disorders. Epidemiological data on vitamin D status in the Polish population are limited. The aim of the study was to evaluate the vitamin D status in patients hospitalized in the surgical ward. Serum levels of 25-hydroxyvitamin D (25(OH)D) were measured from June to November 2017, in 66 patients (44 (66.67%) women, 22 (33.33%) men) aged 22-87 years (the mean age 57.67±15.62 years old) admitted to the Department of General and Oncological Surgery, Medical University of Lodz, Poland. Levels of 25(OH)D were determined using chemiluminescent microparticle immunoassay (CMIA). The mean 25(OH)D level in the studied population was 19.58±6.98 ng/ml (range, 4.80 to 43.20 ng/ml); 56.06% of the patients had 25(OH)D levels of less than 20 ng/ml; 36.36% had suboptimal levels of 20 to 30 ng/ml; and only 7.58% demonstrated the optimal levels of 30 to 50 ng/ml. In the group with thyroid disease: 54.76%, 38.10%, and 7.14% of patients, respectively. There were no statistical differences in the 25(OH)D level depending on gender, age, Body Mass Index (BMI), season of the year and in groups of patients with thyroid disease and other diagnosis. No statistically significant correlation was observed between the vitamin D level and age, weight and BMI. Due to the common vitamin D deficiency in surgical patients, widespread vitamin D supplementation is necessary even in the summer months.

Authors:
Anna Grzegory, Lech Pomorski

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