Review of acne treatment options in pregnancy

Abstract: Acne is a chronic disease in which a dysfunction of the pilosebaceous apparatus of the skin is accompanied by excess sebum production. It may be clinically classified as mild, moderate and severe. Although many effective treatments against acne exist, their known and unknown effects on embryogenesis prevent doctors from prescription to pregnant women. Another factor hindering efficient treatment would be the uncertainty regarding acne course in a gravid. The following review summarizes topical and oral therapies, as well as procedure-based therapies, considering the severity of acne in patients. It also highlights the pathogenesis of acne, drugs’ mode of action and the need for further research. Medical databases were used in order to retrieve articles regarding treatment of acne in pregnant women. This research shows that in all trimesters there is a safe acne treatment option. Concomitant therapies are thought to be more effective in combating acne, which may result in decreasing the number of medicines taken and/or applied to the skin and, hence, diminishing their side effects. In spite of an abundance of treatment options for adult women, lack of complete and trustworthy evidence-based data for pregnant women forces dermatologists and gynaecologists to rely on the current guidelines, which are written based on limited data. More research on targeting acne in pregnant women, including procedure-based therapies as well as delving into the psychological aspect of pregnant’s wellbeing is needed.

Authors:
Patryk Rudzinski, Inga Lopuszynska, Joanna Kacperczyk-Bartnik, Pawel Bartnik, Agnieszka Dobrowolska-Redo, Ewa Romejko-
Wolniewicz

Download this article

Comments are currently closed.