Pregnant women with pre-existing diabetes mellitus type 2 differ from those with diabetes mellitus type 1

Background: Type 2 diabetes has reached epidemic proportions in recent years. The aim of this study was to compare perinatal outcomes in type 2 and type 1 diabetic patients. Materials and Methods: Maternal and fetal outcomes were compared between 62 pregnant women with type 2 pregesta- tional diabetes mellitus and 448 pregnant women with type 1 diabetes who delivered in the University Hospital of Warsaw from 2000 to 2011. Results: Women with type 2 diabetes were older, more overweight prior to pregnancy (BMI 29.3 vs 24.2 kg/m2, p<0.0001), gained less weight during pregnancy and presented with hypertension during pregnancy. The patients with type 2 diabe- tes exhibited lower 1-hour postprandial glycemia levels (104.7 vs 117.4 mg/dL, p<0.001) in the 3rd trimester and lower mean glycemia levels during labor (89.9 vs 107.8 mg/dL, p<0.001). The durations of the pregnancies of these patients were significantly longer (37.1 vs 36.3 weeks, p<0.05). Neonates of mothers with type 2 diabetes were significantly less likely to exhibit low 1st-minute Apgar scores (3.6% vs 18.1%, p<0.05). Conclusions: Pregnant women with type 2 diabetes mellitus present with more risk factors for metabolic syndrome such as hypertension and obesity and exhibit better metabolic control during the 3rd trimester of pregnancy.

Author:

Aneta Malinowska-Polubiec, Ewa Romejko-Wolniewicz, Agnieszka Sotowska

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