Pregnancy after cervical conization – a literature review

Abstract: Cervical intraepithelial neoplasia (CIN) is a precancerous stage of cervical cancer, one of the most easily preventable cancers in women. It is treated with conization, a procedure that can be performed using various methods. Because CIN is often diagnosed in women of reproductive age, there is a strong need to study the consequences of conization for patients planning future pregnancies. According to different studies, this procedure may result in adverse pregnancy outcomes such as preterm delivery, low birth weight and increased perinatal mortality. Many factors can influence these complications, including a particular method of conization, the size of the lesion and a woman’s previous obstetric history. Subfertility is yet another, often researched potential complication of conization. Regardless of the extent of complications, it is proven that conization does influence future pregnancies, thus a careful clinical approach for patients with a history of this procedure is required.

Kinga Grzelak, Joanna Kowalczyk, Joanna Kacperczyk-Bartnik, Pawel Bartnik2#, Agnieszka Dobrowolska-Redo, Ewa Romejko-Wolniewicz

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