High Risk Pregnancy of a Woman With Liver Transplant Failure – Case Report

Abstract: Along with the progress of transplantation medicine, the number of liver transplant recipients has gradually increased in the last decade. Among different indications and clinical run, also some young females have been given a chance to live, become pregnant and give birth to a healthy child. However, pregnancy in liver recipients is associated with increased risk in the post transplant run, both in respect of graft failure and the fetus. A 22-year-old woman after two liver transplantations: first due to the secondary biliary cirrhosis induced by biliary atresia, and second for multiple complications (acute rejections, recurrent cholangitis and the development of AIH), was considered for the third liver transplantation. Shortly after four- month hospitalization, during the outpatient visit, the patient informed about being 7 weeks pregnant. Despite high risk for her and child, the woman did not consent to abortion. Throughout the pregnancy the patient was hospitalized several times because of cholangitis, cholestasis, deepening anemia and thrombocytopenia. Due to the worsening condition of the patient, a decision was made to terminate the pregnancy in 29th week with cesarean section. A healthy son was born, 1320/41, 8 points APGAR score. The described case report shows that with proper cooperation of gynecologist and transplantologist, as well as determination of the recipient it is possible to monitor the pregnancy even during liver transplant failure.

Authors:

Karolina Kuczborska, Jolanta Gozdowska, Marek Pacholczyk, Olga Tronina, Bronisława Pietrzak, Magdalena Durlik

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