Infective endocarditis caused by dental problems correlated with bicuspid aortic valve

Abstract:The aim of the study was to emphasize the importance of prophylaxis of infective endocarditis. Also, the influence of heart failure and bacterial etiology on the treatment was analyzed. This study presents a case report of a patient who was suffering from IE. He was treated in the Cardiology Ward at the Medical University of Lublin. 47-year-old man has resected his tooth in a dental surgery. After a few days at home, he presented non-specific symptoms like fever and chest pain. Bicuspid aortic valve was diagnosed at the Cardiology Ward. Furthermore, vegetation on aortic valve was recorded in echocardiography. That is why IE diagnosis was made. After the therapy with Vancomycin, vegetation on aortic valve was still present. Regurgitation in 3rd state was developed by the patient. New valve was implanted. A few days after operation the patient had subfebrile state. He was treated with Vancomycin and Clindamycin. Currently, he is receiving ciprofloxacin as prophylaxis of IE. Heart failure is a risk factor of IE. These patients should get antibiotic prophylaxis before dental surgery. Patients with heart defect can develop more severe type and treatment in these cases is more difficult. Everyone should undergo non-specific prophylaxis of infective endocarditis. Read full text »

How stress and anti-stress remedies influence bone health

Abstract:Various factors affect the increased risk of skeletal system disorders in the modern society. Chronic stress can be regarded as one of the causes of greatest importance. Epidemiological studies conducted by the World Health Organization (WHO) indicate that the level of stress in the society is constantly increasing. This phenomenon is particularly apparent in developed countries. Bone tissue loss affects not only the elderly, but also people of younger age. Studies have shown reduced bone mineral content (BMC) and bone mineral density (BMD) in people exposed to chronic stress and suffering from depression. These facts can be explained through the mechanism of action of glucocorticoids (GCs) on the bone. It reduces the content of inorganic substances in the bone, thereby weakening its strength. Additionally, important factors causing BMC and BMD to decrease include usage of drugs such as antidepressants, as well as addictions such as smoking. Metyrapone, an inhibitior of cortisol synthesis, has been found to increase serum BMC and osteocalcin (OC) levels and to promote bone formation. Moreover, Alzheimer’s disease (AD) patients using rivastigmine arebe at lower risk of developing hip fracture. Read full text »

Understanding tokophobia phenomenon as a key to proper management

Abstract: Tokophobia also known as fear of childbirth (FOC) becomes a frequent psychiatric indication to Caesarean section which makes it a rising problem of current obstetrics. Patients with FOC may suffer from additional psychiatric conditions such as depression. Women with higher risk of developing tokophobia are those with immense levels of fear of pain, young, with low educational level, poor socio-economic status, low self-esteem and lack of proper knowledge concerning peripartum period. History of unfortunate events during previous deliveries or illness of the older child are also associated with more frequent occurrence of FOC. Adequate management of FOC focuses on implementing psychotherapy. Symptoms of FOC can be decreased by means of qualified and trustworthy medical staff during labor or support from a closely related person. Secondary tokophobia can be prevented by minimalisation of negative experience during the first birth. If tokophobia is the symptom of depression, the underlying illness should be treated. Tokophobic patients are more prone to experience higher levels of pain during labor, which makes peripartum pain management harder for clinicians. FOC is one of the main reasons for performing caesarean delivery on maternal request (CDMR), which may lead to post-operative complications. Research shows that FOC is related to anxiety concerned with lower self-esteem due to changes occurring in women’s body during pregnancy and delivery. Learning and understanding the reasons behind tokophobia might lead to reducing the number of patients suffering from this condition and in consequence minimalizing the number of performed CDMR. Read full text »

Microcephaly associated with Zika virus infection – prevention, diagnosis and treatment

Background: Zika virus (ZIKV) is a mosquito-borne flavivirus, first identified in Uganda in 1947 in monkeys by researchers monitoring yellow fever. Later virus was identified in humans in 1952 in Uganda and the United Republic of Tanzania. Outbreaks of ZIKV disease have been recorded in Africa, the Americas, Asia and the Pacific. From the 1960s to 1980s, human infections were found across Africa and Asia, typically accompanied by mild illness. The first large outbreak of disease caused by Zika infection was reported from the Island of Yap (Federated States of Micronesia) in 2007. The next epidemic of ZIKV infection was reported in 2015 in South and Central America and the Caribbean. Read full text »

Meckel’s diverticulum resection as a part of Emergency General Surgery – single centre experience in years 2006-2014.

Background: An emergency surgery is a medical procedure that must be performed immediately to solve the patients’ health problem successfully. A delay of this medical procedure could result in a death or a permanent impairment of the health. An emergency surgery can be also defined as a surgery which is required to be performed in case of an acute threat to life of an organ, limb or tissue caused by an external trauma, acute disease process, acute exacerbation of a chronic disease process or complication of a surgical or other interventional procedure. Scott and co-workers [1] analysed 3.1 million of patients admitted to the hospital due to acute indication and they reported that emergency general surgery (EGS) represents 11% of admissions. EGS includes: cute appendicitis, peritonitis, bowel obstruction, acute mesenteric ischemia, gastrointestinal perforation or bleeding, acute cholecystitis, irreducible or incarcerated hernias, injuries after accidents e. g. organ fractures, intentional ingestion of foreign bodies or poisonous substances. Read full text »

The Prevalence Of Mycoplasma In Pregnant Women’s Genital Tracts Delivering In TERTIARY Hospital

Background: The aim of this study was to evaluate the prevalence of Mycoplasma hominis and Ureaplasma urealyticum among pregnant women and an attempt to identify risk factors for maternal infection and assessment of the impact of infection on perinatal outcomes. Material and methods: Patients included into the analysis were divided into 2 groups. The first group consisted of 97 (78.9%) women who had not isolated the strains of Mycoplasma, and the second group of 26 (21.1%) women who had isolated a strain of Mycoplasma. Results: Women who had isolated strains of Mycoplasma were significantly younger (p=0.0031), less frequently completed higher education (p=0.0163), less frequently were married (p=0.0061). Women who were not classified with Mycoplasma were more frequently multiparas (p=0.012) and were more likely to have previous caesarean birth (p=0.022). The groups did not differ significantly in terms of gestational age at birth, the incidence of premature rupture of membranes, intrauterine infection, the percentage of women who gave birth vaginally, the birth weight of newborns and the condition of the newborns after delivery. The neonatal respiratory support type nCPAP was more frequently applied to the babies born to mothers who had isolated Mycoplasma. Conclusions: Based on the survey results and data from the world literature, it can be concluded that women with pre-term labour and PROM should be tested for Mycoplasma colonization and the newborn should be observed primarily in terms of complications caused by respiratory tract. Colonization with Mycoplasma in term pregnancy does not impact significantly maternal and neonatal outcome. Read full text »

Recurrent incisional hernia sublay repair with fully reabsorbable monofilament mesh – a case report

Incisional hernia is the most common indication for reoperation after abdominal surgery. Mesh hernioplasty is almost a gold standard of treatment, associated with the low recurrence rate. Study presents a case of usage of a fully reabsorbable mesh for successful sublay hernioplasty in recurrent incisional hernia with a past history of many wound complications.
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Impacted uterine myoma in a 14 week pregnant patient

Uterine myomas are some of the most frequent neoplasms in women in the reproductive age. The frequency of uterine myomas in pregnancy varies between 0.1 and 3.9 %. The pregnancy in a woman with uterine myomas is usually uncomplicated, but in 10% of them, the myomas may cause symptoms. The study presents the case of a pedunculated submucosal myoma impacted in the rectouterine pouch in a woman 14 weeks pregnant.
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Fragments od bacterial DNA presence in hemodialisis patients’ blood-preliminary report

Cardiovascular disease (CVD) accounts for most of morbidity and mortality in patients with end-stage renal disease treated by chronic hemodialysis. The idea that inflammation state present in uremia plays an important role in the development of atherosclerosis has enjoyed much attention. We have investigated therefore pos- sible presence of bacterial DNA in the blood of chronically hemodialyzed patients. There were retrospectively studies of 59 patients without any signs of active infection, who had been undergoing intermittent HD. In 54 among 59 investigated DNA blood samples from HD patients we were able to detect a DNA fragment about 790 bp in length, consistent with the presence of 16sRNA bacterial DNA. Bacterial DNA could not be detected in any of the samples from control subjects. We were not able to detect bacterial DNA in any of 9 investigated dialysate samples although in 4 blood samples of these patients bacterial DNA encoding ribosomal RNA was observed. Bacterial DNA is detectable in blood of HD patients. This might be one of the inflammatory stimuli.
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Dengue, for apparatus and systems

In daily clinical practice we are all familiar with the word „ dengue „ making us think of an acute febrile illness.In order to obtain an overview of the aforementioned, we dengue to various organ systems of human body.
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