Antibiotic resistance – only the most adaptable to changes will survive

Abstract: Antibiotic resistance is a growing problem of the last decade. Excessive and incorrect use of antibiotics has led to a global public health crisis: the emergence of antibiotic-resistant strains that hamper the proper treatment of bacterial infections. Alarm Pathogens are the most dangerous microorganisms which are resistant to all of the available antibacterial drugs. The phenomenon of acquiring antibiotic resistance is mainly caused by horizontal gene transfer, however mutations of genetic information and vertical transfer of resistance genes are not insignificant. The main mechanisms that the microorganisms use in an unfavorable environment, enriched with an antibiotic, are the enzymatic hydrolysis of a molecule of a chemical compound, the enzymatic modification of the antibiotic molecule, the ’by-pass’ reaction and efflux. The conscious use of one of the greatest medical inventions, which are antibiotics, gives a chance to reduce the population of alarm pathogens.

Bozena Czubat, Magdalena Antczak, Sabina Galiniak

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