Multiple Rectal Ulcers (28 of 110)
Case description
Endoscopic biopsies are crucial in the initial evaluation of
ulcerative colitis, to accurately exclude self-limited colitis,
and to differentiate ulcerative colitis from Crohn's disease.
Histologic findings in early stages of ulcerative colitis are
characterized by mucosal infiltration by acute inflammatory
cells, including neutrophils, lymphocytes, plasma cells, and
macrophages. Neutrophilic infiltration of crypts leads to
cryptitis and crypt abscesses. Due to the nonspecific
inflammatory findings, it may be difficult to distinguish
ulcerative colitis from acute colitis at this stage.
ulcerative colitis, to accurately exclude self-limited colitis,
and to differentiate ulcerative colitis from Crohn's disease.
Histologic findings in early stages of ulcerative colitis are
characterized by mucosal infiltration by acute inflammatory
cells, including neutrophils, lymphocytes, plasma cells, and
macrophages. Neutrophilic infiltration of crypts leads to
cryptitis and crypt abscesses. Due to the nonspecific
inflammatory findings, it may be difficult to distinguish
ulcerative colitis from acute colitis at this stage.
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