A 37-year-old man presented with chronic non-specific gastrointestinal tract symptoms including rectal bleeding. Colonoscopic examination showed a mass-like lesion in the descending colon with ulcerated surface. However, the pathological examination of biopsy taken from the lesion did not reveal any neoplastic process. Abdominopelvic computed tomography scan showed a giant transverse colon lipoma with suspicious feature of intussusception in descending colon which had a mass-like appearance on colonoscopy. The patient underwent surgical intervention, with a successful recovery after surgery. Key words:by Ahmad Hormati in Shahid-beheshti-hospital, Qom, Iran
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