New option of HIV prevention?

Condom ceases to be the only common method of HIV prevention. As far as ‘dream’ about anti-HIV vaccination is out of range of modern medicine, scientists are looking for new kinds of pre-exposure prophylaxis. A new development of this group is intravaginal ring containing experimental drug – Dapivirine, which is supposed to prevent viral infection. Currently, a large trial is running in five African countries in order to test effectiveness an extended safety of this contraceptive. Results are expected in early 2015. Read full text »

Indomethacin – a new usage as prevention of post-Endoscopic Retrograde Choleangiopancreatography pancreatitis (post-ERCP pancreatitis)

There is a lot of reasons of acute pancreatitis, There are mechanic causes like bile ducts obstruction because of gallstones or Vater pupile stenosis (55%), toxic – alcohol abuse (35%) the other 10% are as well genetic predisposition (PRSS1 tripsinogen mutation) as iatrogenic factors associated with medicaments (diuretics, betablocers, NSAR) or medical procedures, like endoscopic retrograde cholangiopancreatography (ERCP). (3) The pancreatography is the most common, dangerous and expensive complication of ERCP. According to preliminary studies a single doses of rectal indomethacin could prevent post-ERCP acute pancreatitis by the risk group patients.(4) Read full text »