Osteoporosis is a chronic metabolic disease, leading to increased risk of fractures. The essence of its pathogenesis is a disorder in transformation of the bone tissue, associated with osteoclasts and osteoblasts, which is a constant creation of new bone with tissue resorption at the same time. The balance of this process depends on many factors, eg. hormonal, inflammatory, environmental and genetic. Articles, which lay down the role of genetic factors affecting the occurrence of osteoporosis, appeared mostly at the beginning of the 21st century [1]. 
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