Osteosarcoma is the most common primary bone tumour. It is characterized by the presence of the fusiform cells producing a malignant extracellular osteoid. Both, the malignancy and the ability to create metastasis depend on the histological type. Osteosarcoma is an eighth most common tumour in infants with a peak of incidence between 10 and 14 years. Nevertheless, we should not forget that osteosarcoma is also an adult cancer. In this case it can occur either as an idiopathic or as a secondary disease (e.g. to Paget disease).
The absence of bone adhesion for a long time after a fracture is a vital problem for orthopaedist because it may lead to permanent impairment of organ functions, increase in the costs of treatment and discomfort of the patient due to the “bad choice” of the doctor. It is often a indication to start new methods of treatment and employment of drugs which could accelerate healing. Until now, a lot of methods which expedite healing and differently influence the clinical status of the patients were devised. The research of scientists from the University of North Carolina allow to hope that the new and effective weapon in struggling against the lack of bone adhesion will be stem cells. Read full text »