Erythropoiesis stimulating agents (ESA) – the potential risks for patients with Chronic Kidney Disease treated due to anaemia
Since the introduction of recombinant human erythropoietin (rhEPO) to clinical practice it seemed that the problem of anaemia in patients with chronic kidney disease has been brought under control. Further years have produced modifications of particles of rhEPO and led to the synthesis of new medicines – erythropoiesis stimulating agents. These drugs are characterized by longer half-life and the stability of action. However, the results of recent clinical trials carry dangerous conclusions. Despite the improvement of morphological parameters, the reduction of mortality in these patients was not observed.
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