There is a lot of reasons of acute pancreatitis, There are mechanic causes like bile ducts obstruction because of gallstones or Vater pupile stenosis (55%), toxic – alcohol abuse (35%) the other 10% are as well genetic predisposition (PRSS1 tripsinogen mutation) as iatrogenic factors associated with medicaments (diuretics, betablocers, NSAR) or medical procedures, like endoscopic retrograde cholangiopancreatography (ERCP). (3) The pancreatography is the most common, dangerous and expensive complication of ERCP. According to preliminary studies a single doses of rectal indomethacin could prevent post-ERCP acute pancreatitis by the risk group patients.(4) Read full text »

In 1983 in Paris, a virus was isolated. To this day it fills physicians and the public with fear. This small organic molecule has the power of progressive destruction of the body and, consequently, deprival of life. Will the pre –exposure prophylaxis (PrEP)- so keenly supported by the specialists from the Antiviral Drugs Advisory Committee – be accepted by the strict FDA committee? Read full text »

Written for www.physiciansweekly.com by Alex Stagnaro-Green, MD, MHPE

The effects of pregnancy on the thyroid gland are profound. The gland is required to produce a 50% increase in thyroxine (T4) and triiodothyronine (T3). While a healthy thyroid should respond well to pregnancy, women with limited thyroidal reserve or iodine deficiency who become pregnant can develop hypothyroidism. Read full text »

Sirtuins known as Sirt2 proteins are enzymes, NAD+-dependent deacetylases. Seven homologues of sirtuins (SIRT 1-7) were identified in mammals, which differ in location in cells, activity, function. They play an important role in metabolic processes, aging processes, growth and proliferation. Researchers have been working to find possibility of modulation of biological activity in treatment of metabolic diseases or age-related diseases. Read full text »

Alcohol became an important cause of death among patients with type 1 diabetes. This trend is increasing from the 1980s of the last century. The results of the study assessing the risks associated with alcohol consumption were published in the British Medical Journal. Read full text »

Written for www.physiciansweekly.com by Shane J. Nho, MD, MS
Assistant Professor, Division of Sports Medicine
Department of Orthopedic Surgery
Rush University Medical Center
Rush Medical College of Rush University

Tendinitis of the long head of the biceps (LHB) is a common inflammatory tenosynovitis that occurs as the tendon courses along its constrained path within the bicipital groove of the humerus. Despite plenty of research into the anatomy of the LHB tendon, there is still some controversy on the most appropriate management strategies.

Each year, about 10 million people seek medical attention for shoulder injuries, and another 4 million present to physicians with arm injuries. Tendinitis of the long head of the biceps (LHB) is a common inflammatory tenosynovitis, which occurs as the tendon courses along its constrained path within the bicipital groove of the humerus. It typically presents with anterior shoulder pain and is often exacerbated by overuse. In many cases, LHB tendinopathy occurs in combination with other shoulder problems, particularly rotator cuff tendon injuries.Continue reading

Currently, computed tomography (CT) and magnetic resonance imaging (MRI) are the most important imaging examinations. Selection of a suitable diagnostic method is a key factor affecting both, the quality of treatment and the financial situation in health care. The subject of our study was to analyze referrals to CT and MRI examinations, as well as analysis of these examinations’ results. Read full text »

Outcomes of one of the largest clinical trials comparing transcatheter aortic valve implantation (TAVI) to open heart surgery aortic valve replacement (AVR) were published. Non-inferiority of the TAVI procedure has been demonstrated for mortality and overall clinical outcomes (1). Read full text »

The scientific conference devoted to genetic therapy in metachromatic leukodystrophy treatment in late infancy form was held in Paris in April 16-17.2011. It was organized by European Leukodytrophy Association (ELA). This organization supports families of children suffering from leukodytrophy and ELA enables them gaining financial help. Read full text »

Wrtitten for www.physiciansweekly.com by Craig D. Williams, PharmD
Clinical Associate Professor
Department of Pharmacy Practice
Oregon State University College of Pharmacy
Oregon Health & Science University


Craig D. Williams, PharmD, has indicated to Physician’s Weekly that he has worked as a paid speaker and has received grants/research aid from Merck and Co.
Clinicians should take an active role in helping their patients with type 2 diabetes protect themselves from developing cardiovascular disease, or CVD, in the future.


Cardiovascular disease (CVD) has been well documented as a major cause of morbidity and mortality for individuals with diabetes. Adults with diabetes have a two- to four-fold higher risk of CVD when compared with those without diabetes. “The common conditions coexisting with type 2 diabetes—especially hypertension and dyslipidemia— are clear risk factors for CVD,” says Craig D. Williams, PharmD. “Diabetes itself also confers independent risk of CVD.”

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