Familial Adenomatous Polyposis of the Colon (3 of 30)

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13 years ago
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specialty:
Gastroenterology

Case description

Retroflexed view of the enormous stalk of the biggest tumor at hepatic angle. There are several tiny polyps. Findings are indicative of Familial Adenomatous Polyposis (APC), an autosomic dominantly inherited disease characterized by the presence of 100 or more colorectal adenomatous polyps. The development of colon carcinoma is unavoidable if left untreated. This disease is inherited as an autosomal dominant disorder with a 80% to 100% penetrance. Adenocarcinoma is the inevitable consequence of APC unless the colon is removed. Multiple colon malignancies can occur. Colon Cancer has been reported as early as 9 years of age, although the occurrence of malignancy before adolescence is unusual.

tags: familial adenomatous polyposis FAP colon colonoscopy polyp

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