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Esophageal Squamous Cell Carcinoma of the the upper third of the Esophagus (2 of 3 )
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Large and ulcerated carcinoma is displayed. The normal esophagus is lined by stratified squamous nonkeratinizing epithelium. Squamous cell carcinoma arises from this epithelial layer in apparent response to chronic toxic irritation. Alcohol, tobacco, and certain nitrogen compounds have been identified as carcinogenic irritants
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