Gallbladder Adenocarcinoma and litiasis (2 of 13)

Gallbladder Adenocarcinoma and litiasis.

Gross appearance of gallblader carcinoma filling all the cavity and invading the wall.

Although uncommon, carcinoma of the gallbladder (GB) is
the most common primary hepatobiliary carcinoma, is the
fifth most common malignancy of the GI tract, and
predominantly affects older persons with long-standing
cholecystolithiasis. GB epithelial tumors tend to behave
similarly to other GI adenocarcinomas. When the diagnosis
is made incidentally at the time of cholecystectomy,
surgical resection can be curative; however, more
commonly, the tumor is unresectable and rarely diagnosed
preoperatively despite patients' symptoms. Early diagnosis
can improve the clinical outcome and cure rate of GB
carcinoma.